Alexandra Thomas

Alexandra Thomas

  • Clinical Professor, Applied Clinical Sciences
  • Clinical Professor, Internal Medicine - Hematology, Oncology and Blood and Marrow Transplantation, Carver College of Medicine
  • Co-Leader of the Breast MOG, Internal Medicine, UIHC


C32 GH


(319) 356-2425


Dr. Thomas is a Clinical Professor who trained in Medical Oncology at the University of Iowa. Her clinical and academic work focus on improving the lives of patients with breast cancer. She was educated at Princeton University and obtained her medical degree from Johns Hopkins University. She completed residency at Stanford University.

Dr. Thomas has been in the University of Iowa faculty since 2001. She Co-directs the Holden Comprehensive Cancer Center Breast Multi-disciplinary Oncology Group. She serves as the University of Iowa Principal Investigator for NRG, one of the large national cooperative group developing and conducting clinic trials in cancer. She is a member of the ASCO Scientific Planning Committee and serves on several regional and national clinical trials committees. In 2008 Dr. Thomas received an ASCO Merit Award. She also served as the University of Iowa Faculty President from 2014-5.

Research Narrative

Dr. Thomas’ research includes clinical trials as well as translational and population based investigations. In 2010 she initiated the University of Iowa Breast Molecular Epidemiologic Resource. This is a prospectively collected biologic and epidemiologic resource that has now enrolled over 1,000 patients with breast cancer or at high risk for breast cancer.

Dr. Thomas’ investigations have focused on using population datasets to answer questions that arise in clinic. This work involves extensive collaborations the Health Services Research Division. Questions that this work has addressed include, the impact of imaging findings on the decision to pursue contralateral prophylactic mastectomy, surgical decision-making and the study of rare tumors. Additionally, Dr. Thomas acts as the lead clinician on several translation projects with basic scientists, which seek to bring bench-top discoveries into the clinic. This includes studies looking at novel serum markers of breast tumors and treatments for chemotherapy induced neuropathy.