Guohua An

Guohua An

, MD, PhD
  • Assistant Professor, Department of Pharmaceutical Sciences and Experimental Therapeutics / Division of Pharmaceutics and Translational Therapeutics

Office

S227 Phar

Phone

(319) 467-4600

Biography

After receiving her MD from Taishan Medical College and MS in Clinical Pharmacology from Fudan University, Dr. An joined Ruijin Hospital for 2 years as a clinical pharmacist and research scientist. Then she pursued a further study and got her PhD degree in Pharmaceutical Sciences from SUNY at Buffalo. Her graduate research focused on the role of transporter on the pharmacokinetics and pharmacodynamics of anticancer agent. Her research was further expanded after she joined the R&D group of Abbott, where she gained extensive hands on experience in clinical drug development, PK/PD modeling and simulation. Prior to joining University of Iowa, Dr. An has worked at University of Florida as an Assistant Professor for one and half years. Her research interests include building mechanism-based pharmacokinetic and pharmacodynamic modeling of small molecules (such as tysosine kinase inhibitors) and large molecules (such as Epo); understanding the mechanisms of poor brain penetration and offering novel approaches to overcome it; evaluating the transporter- and enzyme-based herbal-drug interactions.

Research Narrative

After receiving her MD from Taishan Medical College and MS in Clinical Pharmacology from Fudan University, Dr. An joined Ruijin Hospital for 2 years as a clinical pharmacist and research scientist. Then she pursued a further study and got her PhD degree in Pharmaceutical Sciences from SUNY at Buffalo. Her graduate research focused on the role of transporter on the pharmacokinetics (PK) and pharmacodynamics (PD) of anticancer agent. Her research was further expanded after she joined the R&D group of Abbott, where she gained extensive hands on experience in clinical drug development, PK/PD modeling and simulation. Prior to joining University of Iowa, Dr. An has worked at University of Florida as an Assistant Professor for one and half years. Dr. An's research interests include building mechanism-based PK/PD modeling of small molecules (such as tysosine kinase inhibitors) and large molecules (such as Epo); understanding the mechanisms of poor brain penetration of small molecule tyrosine kinase inhibitors and offering novel approaches to overcome it; evaluating the transporter- and enzyme-based herbal-drug interactions.