Mickey L Wells

Mickey L Wells

, PhD
  • Director, UI Pharmaceuticals
  • Associate Professor, Department of Pharmaceutical Sciences and Experimental Therapeutics / Division of Pharmaceutics and Translational Therapeutics

Office

G18

Phone

(319) 335-8674

Research Narrative

Mick received his Ph.D. in pharmaceutics (Professor Eugene L. Parrott) from the University of Iowa in 1990. He then began working at Glaxo/Glaxo Wellcome/GlaxoSmithKline as a senior scientist. He worked in product development for 17 years and played a key role in the development of several commercial products including Wellbutrin SR 100 and 200 mg Tablets, Wellbutrin XL 150 and 300 mg Tablets, Epivir Oral Liquid, Zantac 25 mg Effervescent Tablets and Zantac Soft Gelatin Capsules. During this time he also served as an adjunct assistant professor in pharmaceutical sciences at Campbell University School of Pharmacy. He was named co-inventor on numerous patent applications, wrote several book chapters, published a number of papers, and presented numerous podium and poster presentations. Since 2008 he has been serving as Director of University of Iowa Pharmaceuticals, the College of Pharmacy’s cGMP service division. In addition to his responsibilities as Director of UI Pharmaceuticals, Mick is an associate professor of pharmaceutics.

Curriculum vitae

Education
PhD, Pharmaceutics; University of Iowa, Iowa City, IA, 1990
BS, Pharmacy; University of Iowa, Iowa City, IA 1987
AS, North Iowa Area Community College, 1984 

Professional Experience
2008-Present, Director, University of Iowa Pharmaceuticals, College of Pharmacy, University of Iowa, Iowa City, IA
2008-Present, Director, Division of Pharmaceutical Services, College of Pharmacy, University of Iowa, Iowa City, IA
2008-Present, Associate Professor of Pharmaceutics, College of Pharmacy, University of Iowa, Iowa City, IA
2008, Director, Center for Advanced Drug Development, College of Pharmacy, University of Iowa, Iowa City, IA
2005-2008, Manager, Strategic Technologies, GlaxoSmithKline, Inc.
2001-2005, Manager, Product Development, GlaxoSmithKline, Inc.
2000-2001, Sr. Research Investigator, GlaxoSmithKline, Inc.
1998-2000, Adjunct Assistant Professor in Pharmaceutical Sciences, School of Pharmacy, Campbell University, Buies Creek, NC
1997-2000, Research Investigator II, Glaxo Wellcome Inc.
1996-1997, Research Investigator, Glaxo Wellcome Inc.
1995-1996, Group Leader, CIMA Labs Inc.
1994-1995, Senior Associate Scientist, CIMA Labs Inc.
1993-1994, Research Investigator, Glaxo, Inc.
1991-1993, Senior Scientist, Glaxo, Inc.

Awards/Honors
1987 - Graduated with Highest Distinction, 1st in class of 87 students, University of Iowa, College of Pharmacy
1984 - Graduated with Highest Honors, North Iowa Area Community College 

Publications
Wells ML, Williams SO, Sanftleben RA, Balik SB, and Evans BA. Investigation into the dissolution rate increase on storage of Wellbutrin SR 100 mg tablets. AAPS PharmSciTech. 11(1):113-9, 2010.

 Reynolds DW,  McCune JE, Long SG, Ackerman KP, Balik SB, Canoy WL, Facchine KL, Franklin M, Glendenning A, Haan RJ, Mattocks DM, Sides SL, Tang A, Van Horn F, Wells ML and Whitesell G. Solving Tablet Stability Problems Using Forced Degradation. Tablets & Capsules, 5(4): 12-17, 2007.

 Wells ML. Book Review – Pharmaceutical Process Scale-Up. 2nd Ed., M. Levin, Editor, CRC Press, 2006, 538, ISBN: 10 #57444-876, ISBN: 13 #978-1-57444-876-4, Drug Dev. & Ind. Pharm., 32:1227, 2006.

 Wells ML, Balik SB, Crew C, Sanftleben R, and Wood W. Pilot Plant Operation. (2002) Encyclopedia of Pharmaceutical Technology, Marcel Dekker (James Swarbrick, ed.).

 Wells ML, Balik SB, Crew C, Sanftleben R, and Wood W. Pilot Plant Design. (2002) Encyclopedia of Pharmaceutical Technology, Marcel Dekker (James Swarbrick, ed.).

 Trivedi J and Wells ML. Solubilization Using Cosolvent Approach (2000) Water Insoluble Drug Formulation, Interpharm Press (Rong Liu, ed.).

 Williams SO, Long S, Allen J and Wells ML. Scale-Up of an Oil/Water Cream Containing 40% Diethylene Glycol Monoethyl Ether., Drug Dev Ind Pharm., 26(1): 71-77, 2000.

 Wells ML, Lunte C, Boje K, Morris K, Serajuddin A, Kisor D, Pang D, Brunner L, Chow S, Till A, Kompella U, Wurster DE, Aungst B, Handu S, Kotzan J, Dressman J, Gupta V, Parasrampuria D, and Tibbitts  J. Undergraduate Training in the Pharmaceutical Sciences: Where Are We Heading? Roundtable Proceedings from the 1998 AAPS Annual Meeting, Pharm. Tech., Nov. 1999, p. 42-50.

 Wells ML, Suryanarayanan RG, Wyandt CM, Hollenbeck RG, Wurster DE, Allen, Jr. LV, Sechler LE, Lucisano L, Hardison P, Patel K, Shtohryn L, and Kolling W. Will the PharmD Degree Make the Pharmaceutics PhD an Endangered Species?  Roundtable Proceedings from the 1997 AAPS Annual Meeting Pharm. Tech., Sept. 1998, p. 56-66.

 Wells ML, Wood DL, Sanftleben R, Shaw K, Hottovy J, Weber T, Geoffroy JM, Alkire TG, Emptage MR, and Sarabia R. Potassium Carbonate as a Desiccant in Effervescent Tablets. Int. J. Pharm., 152: 227-235, 1997.

 Wells ML, Tong WQ, Campbell IV, JW, McSorley EO, and Emptage MR. A Four Component Study for Estimating Solubilities of a Poorly Soluble Compound in Multisolvent Systems Using a Scheffé-Type Model. Drug Dev Ind Pharm., 22(9&10): 881-889, 1996.

 Nguyen NAT, Wells ML, and Cooper DC.  Identification of Factors Affecting Preservative Efficacy and Chemical Stability through Statistical Experimental Design. Drug Dev Ind Pharm., 21(14): 1671-1682, 1995.

 Wells ML and Parrott EL. Effect of Surfactants on Release of a Highly Water-Soluble Medicinal Compound from an Inert, Heterogeneous Matrix. Journal of Pharm Sci, 81(5): 453-457, 1992.

 Wells ML and Parrott EL. Models for Release of Chlorpheniramine and a Noninteracting Compound from an Inert, Heterogeneous Matrix Containing an Anionic Surfactant. Drug Dev Ind Pharm., 18(3): 265-284, 1992.

 Wells ML and Eugene L. Parrott EL. Effect of Anionic Surfactants on the Release of Chlorpheniramine Maleate from an Inert, Heterogeneous Matrix. Drug Dev Ind Pharm., 18(2): 175-186, 1992.