Associate Professor,
Division of Pharmaceutics
Contact Information:
Division of Pharmaceutics, 208-1
College of Pharmacy
The Dale E. Wurster Center for Pharmaceutical Technology
The University of Iowa
Iowa City, IA 52242
Phone: (319) 335-8836
Email: vijay-kumar@uiowa.edu
Education
1970 BS (Chemistry, Zoology & Botany), Kanpur University
1972 MS (Chemistry), Lucknow University
1976 PhD (Chemistry), Lucknow University
1981 PhD (Chemistry), Concordia University
Professional Experience
2002-DATE Associate Professor; Division of Pharmaceutics, College of Pharmacy, The University of Iowa
1996-2002 Assistant Professor; Division of Pharmaceutics, College of Pharmacy, The University of Iowa
1992-1996 Clinical Assistant Professor; Division of Pharmaceutics, College of Pharmacy, The University of Iowa
1988-1992 Director; Pharmaceutical and Analytical Chemistry, Biocontrol Incorporated
1987-1988 Research Associate; Department of Chemistry, University of Minnesota
1982-1987 Research Associate; Department of Chemistry, University of Virginia
1981-1982 Research Associate; Department of Chemistry, Michigan State University
1980-1981 Postdoctoral Fellow; Department of Pharmaceutics, School of Pharmacy, University of Georgia
1979-1980 Instructor; Department of Chemistry, University of Georgia
Research Interests
Dr. Kumar's current research focuses on carbohydrate polymers, especially cellulosic polymers, and their uses as pharmaceutical excipients, drug carriers, and biomaterials, biodegradable delivery systems, tissue engineering, interpolymer complexes, and drug-excipient interactions.
Recent Publications
RoyChowdhury P, Klemuk S and Titze I, et al, Effects of fabrication parameters on viscoelastic shear modulus of 2,3-dialdehydecellulose membranes-Potential scaffolds for vocal fold lamina propria tissue engineering. Journal of Biomedical Materials Research Part A Vol 88A Iss 3 pp 680-688, 2009.
M. Reus and Kumar V. Comparative Evaluation of Powder and Tableting Properties of Low and High Degree of Polymerization Cellulose I and Cellulose II Excipients, Int. J. Pharm. 337, 202 (2007).
M. Reus and Kumar V. Modified Cellulose II Powder: Preparation, Characterization, and Tableting Properties, J. Pharm Sci. 96, 408 (2007).
M. Reus and Kumar V. Evaluation of Cellulose II Powders as a Potential Multifunctional Excipient in Tablet Formulations, Int. J. Pharm, 322, 31, (2006).
Chowdhury PR, and Kumar V. Fabrication and Evaluation of Porous 2,3- Dialdehydecellulose Membrane as Potential Biodegradable Tissue-engineering Scaffold, J. Biomed. Mater. Res., 76A, 300 (2006).
Yang D, and Kumar V. Study of the Influence of Reaction Conditions on Degree of Substitution, Intrinsic Viscosity, and Yield of Oxidized Cellulose Acetates by Experimental Factorial Design, J. Appl. Polym. Sci., 96, 696 (2005).
.Reus M, Lenz M, Kumar V. and Leuenberger H, Comparative Evaluation of Mechanical Properties of UICEL and Commercial Microcrystalline and Powdered Celluloses, J. Pharm. Pharmacol., 56, 951-958 (2004).
Kumar V, Powdered/Microfibrillated Cellulose, U.S. 6,821,531 (November 23, 2004).
Kumar V, "Powdered/Microfibrillated Oxidized Cellulose," U.S. 6,627,749 (September 30, 2003).
Kumar V, "Powdered/Microfibrillated Oxidized Cellulose," U.S.6,627,749 (September 30, 2003).
Kumar V. Reus M, and Yang D. Preparation, Characterization, and Tableting Properties of a New Cellulose-based Pharmaceutical Aid, Int. J. Pharm., 235, 129 (2002).
Kumar V and Yang D. Oxidized Cellulose Esters: I. Preparation and Characterization of Oxidized Cellulose Acetates (COOH 20%; DS 1.2-2.3) - A New Class of Biodegradable Polymers, J. Biomater. Sci. Polymer Edn., 48, 403 (2002).
Kang J, Kumar V, Chowdhary PR, Yang D, and Hohl RJ. "Cyclodextrin Complexation: Influence on Solubility, Stability, and Cytotoxicity of Camptothecin, an Antineoplastic Agent," Eur. J. Pharm. Sci., 15, 163 (2002).
Kumar V and Yang T. "HNO3-H3PO4-NaNO2 Mediated Oxidation of Cellulose - Preparation and Characterization of Bioabsorbable Oxidized Celluloses in High Yields and With Different Levels of Oxidation, Carbohydr. Polym., 48, 403 (2002).
Kumar V. "Palatable Drug Granules," U.S. Patent U.S. 6,372,259 (April 16, 2002).
Kothari SH, Kumar V, and Banker GS. "Comparative Evaluation of Powder and Mechanical Properties of Low Crystallinity Celluloses and Commercial Microcrystalline Celluloses and Powdered Celluloses," Int. J. Pharm., 232, 69 (2001).
Kumar V, Kothari S, and Banker GS. "Effect of Agitation Rate on the Generation of Low Crystallinity Cellulose from Phosphoric Acid," J. Appl. Polym. Sci., 82, 2624 (2001).
Zhu L, Kumar V, and Banker GS. "Examination of Oxidized Cellulose as a Macromolecular Prodrug Carrier: Preparation and Characterization of an Oxidized Cellulose-Phenylpropanolamine Conjugate," Int. J. Pharm., 232, 35 (2001).
Kumar V, Kang J, and Yang T. "Preparation and Characterization of Spray-Dried Oxidized Cellulose Microparticles," Pharm. Dev. Technol., 6, 449 (2001).
Kumar V, Kang J, and Hohl RJ. "Improved Dissolution and Cytotoxicity of Camptothecin Incorporated into Oxidized Cellulose Microspheres Prepared by Spray Drying," Pharm. Dev. Technol., 6, 459 (2001).
Kumar V, Kothari SH, and Banker GS. "Compression, Compaction, and Disintegration Properties of Low Crystallinity Celluloses Produced using Different Agitation Rates During Their Regeneration from Phosphoric Acid Solutions," AAPS PharmSciTech, 2 (2) article 7 (2001) (http://www.pharmscitech.com/).
Kumar V and Deshpande GS. "Immobilization of Bovine Serum Albumin on 6-Carboxycellulose, Art. Cells, Blood Subs., Immob. Biotech., 29, 203 (2001).
Kumar V, Yang T, and Yang Y. "Interpolymer Complexation. II. Entrapment of Ibuprofen by in-situ Complexation between Polyvinyl Acetate Phthalate (PVAP) and Polyvinylpyrrolidone (PVP) and Development of a Chewable Tablet Formulation," Pharm. Dev. Technol., 6, 71 (2001).