HHP:4480   Introduction to Human Pharmacology

General pharmacology (e.g., administration, distribution, and elimination of drugs, dose response curves, adverse effects, placebos, homeopathy); pharmacotherapy of selected human diseases, pathophysiologic aspects of the disease, how different classes of drugs modify pathophysiologic effects to restore health or reduce disease's impact; focus on mechanisms of drug actions in humans; adverse effects, pharmacokinetic considerations, drug interactions; how to write prescriptions.

PCOL:2120   Drugs: Their Nature, Action, and Use

Principles of drug action, toxicity; sedatives, stimulants, hallucinogens, narcotics, over-the-counter agents, antibiotics, oral contraceptives. Offered spring semesters.

PCOL:4130   Drug Mechanisms and Actions

Introduction to principles of pharmacology, pharmacologic actions of drugs. Offered spring semesters.

PHAR:1100   Introduction to Pharmaceutical Sciences: Drug Development

Introduction to the drug discovery, development, and approval pathways used in the United States with a specific focus on career pathways related to pharmaceutical development, including the natural and biomedical sciences, clinical, regulatory and legal affairs, sales and marketing, and business development.

PHAR:1111   Need A New Drug?

Introduction to drug discovery, development, and approval process in the United States with a focus on preclinical and clinical development activities and the role of the FDA and other regulatory bodies in the approval and oversight of available drug products.

PHAR:1200   Medicines That Changed the World

Herbal remedies and ancient traditional medicines have led to the discovery of life-saving drug therapies; as science has evolved, how the discovery of other important medicines have come about through advances in chemistry and biology and now through advances in computer science and informatics; students learn about the discovery history of some of the most important drug therapies of the 20th and 21st centuries and how those discoveries are leading to even more important, life-saving treatments.

PHAR:4146   Drug Disposition and Pharmacokinetics

An introduction to drug absorption, distribution and elimination processes controlling overall drug exposure in humans. Basic quantitative measurements will be presented and used to demonstrate the influence of drug properties and physiologic action on drug disposition.

PHAR:4501   Basic Principles of Toxicology

Basic principles and mechanisms of toxicology as it relates to drugs and environmental agents.

PHAR:4502   Toxic Agents

Specific toxicants and toxicity not related to organ systems including carcinogenesis and oxidative stress; clinical toxicology and antidotes.

PHAR:4503   Organ and Organ Toxicity

How toxicants, such as drugs, interact with organ systems and organisms.

PHAR:4512   Principles of Drug Discovery

Focus on understanding drug targets as receptors, receptor theory, drug discovery, and new drug approval processes; areas of novel drug target identification, pharmacological characterization of new drugs, G protein coupled receptors as targets, and analysis of drug-receptor interactions.

PHAR:4537   Principles of Drug Metabolism

Principles of drug metabolism based on current knowledge of involved enzymes.

PHAR:4800   Chemical and Biophysical Properties of Drugs

Introduction to design of drug molecules based on an understanding of drug-like properties including chemical reactivity and structural optimization; minimization of potentially toxic biotransformations; optimization of absorption; screening methods for selection and classification of optimized molecules.

PHAR:6700   Advanced Pharmacokinetics and Pharmacodynamics

Application of pharmacokinetics and pharmacodynamics principles in pharmaceutical research.