Pharmaceutical Sciences and Experimental Therapeutics faculty are committed to impactful, diverse and innovative programs of scholarship focused on drug discovery and drug delivery. We strive to maintain a creative and supportive environment to train the next generation of biomedical/pharmaceutical scientists and healthcare professionals.  
--Jonathan A Doorn, Department Chair
The Department of Pharmaceutical Sciences and Experimental Therapeutics has two focus areas and two PhD subprograms.

Drug Discovery and Experimental Therapeutics is a discipline that encompasses drug discovery and the development of novel therapeutics. Research at Iowa includes a strong synthetic medicinal chemistry component, including the development of new synthetic methodologies to construct anti-infective, anti-cancer and anti-viral agents.  Faculty members are also focused on drug metabolism and carcinogenesis, chemical toxicology, and neurochemistry. Research is being conducted in gene delivery system development and the identification of novel targets for anticancer agents and the treatment of central nervous system disorders as well as the discovery of novel pre-therapeutic lead molecules through the use of High Throughput Screening.  Additionally, small molecule drug discovery is achieved through structure-based drug design (SBDD) and computer-aided drug discovery (CADD), with a strong emphasis on enzyme drug targets.

Pharmaceutics' faculty members are investigating the development of novel drug delivery systems for both small and large molecules, including the delivery of genetic material.  Another intense research activity includes the field of tissue engineering, developing and integrating minimally invasive strategies to deliver scaffolds in vivo. Research areas also include physical pharmacy, dosage form development and performance, and industrial/manufacturing pharmacy, as well as the pharmacokinetics and pharmacodynamics of drugs and biological molecules.  Several faculty members are focused on research in drug delivery and targeting, pharmacogenomics, and individualized therapy.  Applied and fundamental research aimed at improving and re-engineering the pharmaceutical product, process design, and development, is yet another focus area.